Sickle cell disease (SCD) is a prevalent type of corpuscular anemia affecting approximately 300,000 babies born each year. The condition is characterized by hemolytic anemia and episodes of microvascular vaso-occlusion leading to ischemia-reperfusion injury and organ damage. Current treatment options for managing complications include the use of hydroxyurea (HU). In high-resource countries, allogeneic hematopoietic stem cell transplant (HSCT) is a potential cure. However, there are significant risks, including acute toxicity and late effects, e.g., infertility caused by previous gonadotoxic conditioning.
In Munich, images for testicular biopsy samples were captured using PreciPoint M8 Microscope and Scanner. The samples were subsequently analyzed via ViewPoint Virtual Microscopy Viewing Software.
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