Stroke is a leading cause of mortality and adult disability worldwide, with ischemic stroke being the primary form responsible for over 70% of cases in China. The approved treatment for acute ischemic stroke, recombinant tissue plasminogen activator (rtPA), has limitations due to a narrow treatment window and safety issues. Hence, there is an urgent need to investigate and advance alternative therapies for ischemic stroke.
What was M8 Microscope and Scanner Used For?
The researchers used the PreciPoint M8 Microscope and Scanner to obtain TTC–stained samples to interpret the potential protective effect of CAG against ischemic brain injury and determine whether the beneficial effect is associated with the upregulation of SIRT1 in the affected brain tissue.
Where can I find the publication?
To read the entire publication, click on Cycloastragenol upregulates SIRT1 expression, attenuates apoptosis and suppresses neuroinflammation after brain ischemia.